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<div id="m_3506381344355326647m_3882500792968691542m_-2738425513116713815gmail-:1fx"><div id="m_3506381344355326647m_3882500792968691542m_-2738425513116713815gmail-:16q"><div dir="ltr"><div style="color:rgb(49,49,49);word-spacing:1px"><font size="2">As part of the series of seminars <i>"Insalate di Matematica"</i>, <b>Beatrice Ghitti</b>, PhD student at <span style="color:rgb(34,34,34);word-spacing:0px">the Università degli Studi di Trento</span><font style="word-spacing:0px" color="#313131"><span style="word-spacing:1px">, will deliver a talk. </span></font></font></div><div style="color:rgb(49,49,49);word-spacing:1px"><font size="2">
According to the current Covid regulations, the seminar will be held in a <u>hybrid mode</u> <b>(more information below)</b>.
</font></div><div style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><br></font></div><div style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><span style="color:rgb(34,34,34)">Here the details:</span></font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><br></font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><u>Date and time</u>: <b>16th December 2021, 2:00 pm (CET)</b></font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><u><br></u></font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><u>Title</u>: <i><span style="background-color:rgb(241,194,50)">"Towards computationally efficient and accurate blood flow simulations in the entire cardiovascular system<span style="color:rgb(34,34,34)">"</span></span><br><span style="color:rgb(34,34,34);background-color:rgb(241,194,50)"></span></i></font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><br></font></div><div dir="ltr"><font size="2"><u style="color:rgb(49,49,49);word-spacing:1px">Abstract</u><font color="#313131"><span style="word-spacing:1px">: In the last decades, mathematical modeling and simulation of blood flow have become of primary importance in different contexts, from basic research to clinical practice, employing different levels of model complexity and sophistication, from lumped-parameter (0D) to distributed (1D and 3D) models. A relevant contribution in this field is the global, closed-loop, multiscale mathematical model of the entire human circulation developed by M ̈uller and Toro (2014) and recently extended (2021). Modeling blood flow in complex networks and cardiovascular models can result in computationally expensive simulations, posing the need for strategies and numerical methods to perform accurate and efficient simulations. In this contribution, I will first present the Müller-Toro global model and, in this framework, discuss the major challenges related to the 1D blood flow modeling. After that, I will focus on one of the main model components, the vascular (arterial and venous) networks, by describing both the 1D and 0D nonlinear models for blood flow. I will finally present a novel methodology we have developed to construct hybrid 1D-0D networks of vessels and to perform computationally efficient and accurate blood flow simulations in such networks. This methodology is based on high-order numerical coupling strategies and a-priori model selection criteria which provide the best possible trade-off between accuracy of the results and computational cost of the simulations.</span></font><span style="color:rgb(0,0,0);font-family:Roboto,-apple-system,BlinkMacSystemFont,"Apple Color Emoji","Helvetica Neue",sans-serif"></span></font></div><div dir="ltr"><font size="2"><span style="color:rgb(0,0,0);font-family:Roboto,-apple-system,BlinkMacSystemFont,"Apple Color Emoji","Helvetica Neue",sans-serif"><br></span></font></div><div dir="ltr"><div dir="auto"><font size="2"><u style="color:rgb(49,49,49);word-spacing:1px">Keywords</u><font color="#313131"><span style="word-spacing:1px">: Cardiovascular system; Blood flow; Multiscale modeling; Reduced-order models; High-order numerical schemes; Model selection criteria; Computational efficiency.</span></font><span style="color:rgb(0,0,0);font-family:Roboto,-apple-system,BlinkMacSystemFont,"Apple Color Emoji","Helvetica Neue",sans-serif"></span></font></div><div dir="auto"><font size="2"><br></font></div><div dir="auto" style="word-spacing:1px"><font size="2" color="#313131"><br></font></div><div style="word-spacing:1px"><font size="2" color="#313131"><b><u>Information to attend in room 3014<br></u></b></font></div>
<div style="word-spacing:1px"><font color="#313131">The
seminar will take place in room 3014, at the building U5-Ratio,
Università degli Studi di Milano Bicocca. Unfortunately, only a limited
number of participants is allowed</font><span style="color:rgb(49,49,49)"> </span><span style="color:rgb(49,49,49)">in presence, hence reservation is mandatory. You can reserve at the following link: </span><a href="https://sites.google.com/view/insalate-di-matematica/reservation?authuser=0" target="_blank">https://sites.google.com/view/insalate-di-matematica/reservation?authuser=0</a></div><div style="word-spacing:1px"><font color="#313131">We also remind that you will be required to exhibit your green pass at the entrance of the building.</font></div>
<div style="word-spacing:1px"><font size="2" color="#313131"><br></font></div><div style="word-spacing:1px"><font size="2"><b style="color:rgb(49,49,49)"><u>Information to attend online</u></b></font></div><div style="word-spacing:1px"><font size="2" color="#313131">The seminar will be streamed via</font><font size="2" color="#313131"> Google Meet platform at the following link: <a href="https://meet.google.com/fte-wkvi-dmq" target="_blank">https://meet.google.com/fte-wkvi-dmq</a></font><font size="2"><span style="font-family:Roboto,Arial,sans-serif;letter-spacing:0.3px;white-space:nowrap"></span></font></div><div dir="auto"><font size="2"><i><b>** We inform you that the talk will be recorded and uploaded on our website. If you join the talk <u>after the starting time</u>, we kindly ask you to ensure that <u>your microphone and webcam are turned off</u> **</b></i><br></font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><br></font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2">You can find the poster of the event in the attachment. We are looking forward to seeing you! </font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><br></font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2">For further information, please visit our website: <a href="https://sites.google.com/view/insalate-di-matematica" target="_blank">https://sites.google.com/view/insalate-di-matematica</a> or contact us at <a href="mailto:insalate.matematica@unimib.it" target="_blank">insalate.matematica@unimib.it</a>.</font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><br></font></div><div dir="auto" style="color:rgb(49,49,49);word-spacing:1px"><font size="2"><br>The organizers: Luigi Appolloni, Andrea Bisterzo, Alberto Cassella, Francesca Cottini, Ludovico Marini</font></div></div></div><div>
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